1.
Condensation Reaction of Various Nucleophiles with Important
Derivatives of 3-Formylchromones
Sharad N. Shelke1*, Kisan M. Kodam2,
Nilesh G. Salunkhe1 and Bhausaheb K. Karale1
1
P.G. & Research, Department of Chemistry, S. S. G. M. College,
Kopargaon,
Dist-Ahmednagar- 423 601 (India).
2 Department of Chemistry, University of Pune, Pune-411
007 (India)
Abstract:
Various substituted 3-formylchromones were treated with acid
hydrazide A to form corresponding hydrazones 3.
Corresponding salicylol pyrazoles 5 were synthesized from
hydrazones 3 by treating with potassium hydroxide.
Pyrimidine 6 synthesized from
4-((substituted-4-oxo-4H-chromon-3-yl)methylene)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-ones
2 were synthesed by treating with guanidine in presence of
alcoholic potassium hydroxide.
3-(2-Hydroxyphenyl)-1H-pyrazole-4-carboxaldehyde 7 were
obtained from 3-methyl-4-[(chromon-3-yl)-methylene]-1-phenyl
pyrazolin-5-(4H)-ones 2 by treating with hydrazine hydrate.
Keywords: 3-Formylchromone, Salicyloyl pyrazoles, Guanidine,
Pyrazole.
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