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15.
Synthesis, Characterization and Antibacterial Activity of Some Novel
3,8-Diaryl-5H-s-Triazolo (3,4-b) Isoxazolo
(5,4-e)-1,3,4-Thiadiazines
A.K. Yadav and D. Singh
Synthetical Organic Research Lab, Department of Chemistry,
T.D.P.G. College, Jaunpur, (U.P.) India, PIN–222 002
E-mail :
yadav_ajay002@rediffmail.com
Abstract:
3,8-Diaryl-5H-s-triazolo (3,4-b) isoxazolo
(5,4-e)-1,3,4-thiadiazines (3) have been synthesised by the
condensation of 4-bromo-3-aryl-isoxazolo-5-(4H)-ones (1) and
3-aryl-4-amino-5-mercapto-1,2,4-triazoles (2) in the presence of
pyridine. The synthesised compounds have been screened for their
antibacterial activity against S. aureus and E. coli.
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