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6.
Synthesis, Spectral Analysis and Pharmacological Evaluation of Some
New Imidazole Derivatives
Nitin Kumar*, Sushma Drabu#, Asif husain1
# M.S.I.P., C-4, Janak Puri, New Delhi, India.
1 D/o Pharmaceutical chemistry, F/o Pharmacy, Jamia Hamdard, New
Delhi, India.
*Pharmaceutical Chemistry Research Lab., D/o Pharmaceutical
Technology,
MIET, NH-58, Bypass Road, Baghpat Crossing, Meerut- 250005, U.P.,
India.
Tel: +91-1212439019, 2439057, Fax: +91-1212439058, Mob.:
09310497960, E. mail:
nitinvermakr@yahoo.com
Abstract:
Di & tri substituted imidazoles
were prepared by condensing phenylglyoxal with different aryl
aldehydes in presence of ammonium acetate and glacial acetic
acid. All the di and tri substituted imidazoles were
characterized by spectral analysis i.e. 1HNMR and
Mass spectral data. All the synthetic compounds were screened
for there anti-inflammatory and anti bacterial activity.
KEY WORDS:
Imidazole, Phenyl glyoxal, anti-inflammatory and
anti microbial.
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