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4.
Synthesis, Characterization and Bio- Activity of Metal Complexes of
Isatin Derivative
G. Valli * & J. Vinnarasi
The Standard Fireworks Rajaratnam College for Women, Department of
chemistry, Sivakasi-626123. Virudhunagar District, Tamil Nadu State,
India.
* Corresponding author: Email: mrs.valliravichandran@gmail.com
VINNISKY@gmail.com
Abstract:
A new series of transition metal complexes of Cu(II), Mn(II),
Cd(II), Zn(II), Ni(II) and Co(II) derived from Isatin -
anthranilic acid Schiff base and mixed ligand metal
complexes have been synthesized and characterized in the
light of spectral studies like IR, UV, and 1H- NMR. The
synthesized metal complexes have been screened for their
invitro antibacterial activities by zone of inhibition
method against Proteus vulgaris, Bacillus subtilis,
Pseudomonas aeruginosa, Escherichia coli, Staphylococcus
aureus, Klebsiella pneumoniae, Micrococcus and Salmonella
typhi “H”. The antibacterial screening showed that cadmium
complex possesses higher activity towards Staphylococcus
aureus.
Key words: Isatin,
Anthranilic acid and antibacterial activity.
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