16- Charge Transfer Studies Between Paracetamol And Nucleic Acid Bases

*Anwar S El-Shahawy, Seddique M Ahmed, Nager Kh Sayed

Chemistry Department, Faculty of Sciience, Assiut University, ASSIUT- EGYPT

 *Corresponding author: e-mail: anwarshahawy@yahoo.com

 Abstract: From INDO calculations, it has been found that the electron affinity of paracetamol is higher than those of the nucleic acid bases therefore paracetamol molecule may withdraw an electron from one of the nucleic acid bases in the humanbeing  cell to form charge transfer complex to render the cell behaves abnormally which is known as cancer. Extending our work to involve caffeine, it has been concluded that the energy of electron transfer with paracetamol is lower than the energies of electron transfer with the nucleic acid bases in the humanbeing cell. Therefore it can be advised to drink one cup of coffee in the morning to avoid cancer because the caffeine molecules protect the humanbeing cell from any electron transfer with any cancer suspecting agents.

Keywords: INDO, Paracetamol, Nucleic acid-bases, Caffeine

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